... Medications that block androgen production include abiraterone (Zytiga) and ketoconazole.Medications That Prevent Androgens From WorkingAndrogens affect prostate cancer cells by attaching to androgen receptors, which are proteins on the surface of the cells. ...
... testosterone levels as much as possible.Doctors may recommend PARP inhibitors for people whose cancer cells have mutations in DNA repair genes, such as BRCA1, BRCA2, or other genes known as homologous recombination repair (HRR) genes.Sometimes these drugs are used alone, but more often they are given alongside hormonal therapy, such as abiraterone (Zytiga ...
PARP Inhibitors for Prostate Cancer: What To Know About Targeted Therapy
... testosterone levels as much as possible.Doctors may recommend PARP inhibitors for people whose cancer cells have mutations in DNA repair genes, such as BRCA1, BRCA2, or other genes known as homologous recombination repair (HRR) genes.Sometimes these drugs are used alone, but more often they are given alongside hormonal therapy, such as abiraterone (Zytiga ...
... An example is abiraterone (Zytiga). Testosterone is made in many places in the body, like the adrenal glands and the prostate cancer tumor itself. Androgen synthesis inhibitors stop testosterone production in all of these places. They’re usually used for people with advanced or metastatic prostate cancer.5. ...